Artist Conk Mushroom vs. Diabetic Complications

By Dr. Markho Rafael

The white underside of the mushroom Artist Conk (Ganoderma applanatum) turns brown when bruised and can be intricately etched into detailed carvings, hence the English common name of this ubiquitous American tree fungus.

According to American tree expert David Arora - author of mushroom identification guide Mushrooms Demystified - Artist Conk is "the most common conk in our area [USA]," along with Red-belted Conk (Fomitopsis pinicola). [400] Artist Conks can grow huge and live for 50 years.

Ganoderma applanatum (Artist Conk) grows on nearly all species of hardwood, and even on some conifers such as Douglas Fir. "The only regions where it seems to be absent are those where there aren't any trees!" says Arora. [400]

Historically, Artist Conk was sometimes burned, which produced an insect repellant smoke. It also gives off a pleasant scent. [25]

In 2008, a study by Jeong et al. stated that an isolated compound from Artist Conk "significantly inhibited the growth of solid tumor [Sarcoma-180] and increased the natural killer (NK) cell activity." [401] NK cells, or Natural Killer cells, are white blood cells that form a vital part in the human immune system's cancer fighting arsenal. At least four additional studies have also reported positive findings in regards to the anti-tumor properties of Ganoderma applanatum. [402, 403, 404, 405]

A less commonly studied area when it comes to medicinal mushrooms is their effect on blood glucose levels and diabetic complications. Jung et al. in 2005 reported that an alcohol extract of Artist Conk showed blood glucose lowering properties. [407] This was later confirmed in 2007 when a new study reported an average 22.0% blood glucose lowering effect by a compound isolated from Ganoderma applanatum, as well as a lowering of blood lipids (triglycerides and cholesterol) by 20.3%. [406]

However, the main purpose of the 2005 study by Jung was to assess Artist Conk's effect on inhibiting aldose reductase, an enzyme that's considered responsible for the organ complications seen in diabetics. It is commonly believed that inhibiting aldose reductase in diabetics could have a major effect on decreasing side-effects of diabetes. Jung reports that "these results suggested that G. applanatum [Artist Conk] might possess constituents with anti-diabetic and inhibitory effects on diabetic complications." [407] Two other studies have also found Artist Conk exhibiting significant aldose reductase inhibiting properties. [408, 409]

Moving on to other areas of health, a 2005 paper published findings that Artist Conk extract "could strengthen gastric mucosa barrier," which may come in handy for treating gastric ulcers. [410] Other studies have reported Ganoderma applanatum extract as immune boosting, [25] anti-bacterial, [411, 412, 413] antioxidant, [416] anti-viral, [414] diuretic and anti-parasitic. [415]

Additionally, world renowned medicinal mushroom expert Paul Stamets also includes inflammation and respiratory conditions as two more areas where scientific research on Artist Conk extract have yielded positive results. [134]

Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any medicinal mushroom or herb without prior approval by a medical doctor.

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